벤조디아제핀 이량체, 그의 접합체, 및 제조 및 사용 방법

하기에 의해 나타내어진 구조를 갖는 벤조디아제핀 이량체.화학식 I, Ia, 및 Ib에서의 가변기는 본 출원에 정의된 바와 같다. 이러한 이량체는 특히 항체-약물 접합체 (ADC)에 사용 시에 항암제로서 유용하다. wherein the variables in formulae (I), (Ia), and (Ib) are as defined in the application. Such dimers are useful as anti-cancer agents, especially when used in an antibody-drug conju...

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Main Authors MCDONALD IVAR M, HUYNH TRAM N, GANGWAR SANJEEV, ZHANG YONG, BORZILLERI ROBERT M, CHOWDARI NAIDU S
Format Patent
LanguageKorean
Published 12.09.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract 하기에 의해 나타내어진 구조를 갖는 벤조디아제핀 이량체.화학식 I, Ia, 및 Ib에서의 가변기는 본 출원에 정의된 바와 같다. 이러한 이량체는 특히 항체-약물 접합체 (ADC)에 사용 시에 항암제로서 유용하다. wherein the variables in formulae (I), (Ia), and (Ib) are as defined in the application. Such dimers are useful as anti-cancer agents, especially when used in an antibody-drug conjugate (ADC).
AbstractList 하기에 의해 나타내어진 구조를 갖는 벤조디아제핀 이량체.화학식 I, Ia, 및 Ib에서의 가변기는 본 출원에 정의된 바와 같다. 이러한 이량체는 특히 항체-약물 접합체 (ADC)에 사용 시에 항암제로서 유용하다. wherein the variables in formulae (I), (Ia), and (Ib) are as defined in the application. Such dimers are useful as anti-cancer agents, especially when used in an antibody-drug conjugate (ADC).
Author BORZILLERI ROBERT M
GANGWAR SANJEEV
CHOWDARI NAIDU S
ZHANG YONG
MCDONALD IVAR M
HUYNH TRAM N
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Snippet 하기에 의해 나타내어진 구조를 갖는 벤조디아제핀 이량체.화학식 I, Ia, 및 Ib에서의 가변기는 본 출원에 정의된 바와 같다. 이러한 이량체는 특히 항체-약물 접합체 (ADC)에 사용 시에 항암제로서 유용하다. wherein the variables in formulae (I),...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title 벤조디아제핀 이량체, 그의 접합체, 및 제조 및 사용 방법
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