HETEROCYCLIC COMPOUNDS AND USE THEREOF

• Main Authors: SHIA KAK SHAN, JAN JIING JYH, CHAO YU SHENG, TSOU LUN KELVIN, CHEN CHIUNG TONG
• Format: Patent
• Language: English; Korean
• Published: 27.06.2017
• Subjects: ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM; CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

화학식 (I)의 헤테로사이클릭 화합물이 본원에 기재된다. 또한 상기 헤테로사이클릭 화합물을 함유하는 약학적 조성물과 조혈 줄기세포 및 내피 전구 세포를 말초 순환 내로 동원하기 위해 상기 헤테로사이클릭 화합물을 사용하는 방법이 개시된다. 상기 헤테로사이클릭 화합물로 조직 손상, 암, 염증 질환 및 자가면역 질환을 치료하는 방법이 더 제공된다. Heterocyclic compounds of Formula (I) shown herein. Also disclosed are pharmaceutical compositions containing the heterocyclic compounds and methods of using the heterocyclic compounds to mobilize hematopoietic stem cells and endothelial progenitor cells into the peripheral circulation. Further provided are methods for treating tissue injury, cancer, inflammatory disease, and autoimmune disease with the heterocyclic compounds.