CO-CRYSTALS OF MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

본 개시내용은 N-[2,4-비스(1,1-디메틸에틸)-5-히드록시페닐]-1,4-디히드로-4-옥소퀴놀린-3-카르복스아미드 (화합물 1) 및 공-형성제를 포함하는 공-결정 및 그의 제조 방법에 관한 것이다. 본 개시내용은 추가로 공-결정 형태를 포함하는 제약 조성물, 뿐만 아니라 그를 사용한 치료 방법 및 키트에 관한 것이다. The present disclosure relates to co-crystals comprising N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-o...

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Main Authors CONNELLY PATRICK RAYMOND, FAWAZ MAJED, CAESAR JR. JOHN P, LUSS LUSIS EDUARD, STROHMEIER MARK, ZHANG YUEGANG, MIAO HAI, MCCLAIN BRIAN R, MEDEK ALES, YIN PING, NTI ADDAE KWAME WIREDU
Format Patent
LanguageEnglish
Korean
Published 08.06.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract 본 개시내용은 N-[2,4-비스(1,1-디메틸에틸)-5-히드록시페닐]-1,4-디히드로-4-옥소퀴놀린-3-카르복스아미드 (화합물 1) 및 공-형성제를 포함하는 공-결정 및 그의 제조 방법에 관한 것이다. 본 개시내용은 추가로 공-결정 형태를 포함하는 제약 조성물, 뿐만 아니라 그를 사용한 치료 방법 및 키트에 관한 것이다. The present disclosure relates to co-crystals comprising N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1) and a co-former and methods for their preparation. The present disclosure further relates to pharmaceutical compositions comprising the co-crystal forms, as well as methods of treatment therewith and kits.
AbstractList 본 개시내용은 N-[2,4-비스(1,1-디메틸에틸)-5-히드록시페닐]-1,4-디히드로-4-옥소퀴놀린-3-카르복스아미드 (화합물 1) 및 공-형성제를 포함하는 공-결정 및 그의 제조 방법에 관한 것이다. 본 개시내용은 추가로 공-결정 형태를 포함하는 제약 조성물, 뿐만 아니라 그를 사용한 치료 방법 및 키트에 관한 것이다. The present disclosure relates to co-crystals comprising N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1) and a co-former and methods for their preparation. The present disclosure further relates to pharmaceutical compositions comprising the co-crystal forms, as well as methods of treatment therewith and kits.
Author NTI ADDAE KWAME WIREDU
MEDEK ALES
YIN PING
ZHANG YUEGANG
LUSS LUSIS EDUARD
CAESAR JR. JOHN P
CONNELLY PATRICK RAYMOND
STROHMEIER MARK
FAWAZ MAJED
MCCLAIN BRIAN R
MIAO HAI
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– fullname: ZHANG YUEGANG
– fullname: MIAO HAI
– fullname: MCCLAIN BRIAN R
– fullname: MEDEK ALES
– fullname: YIN PING
– fullname: NTI ADDAE KWAME WIREDU
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Snippet 본 개시내용은 N-[2,4-비스(1,1-디메틸에틸)-5-히드록시페닐]-1,4-디히드로-4-옥소퀴놀린-3-카르복스아미드 (화합물 1) 및 공-형성제를 포함하는 공-결정 및 그의 제조 방법에 관한 것이다. 본 개시내용은 추가로 공-결정 형태를 포함하는 제약 조성물, 뿐만 아니라 그를...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title CO-CRYSTALS OF MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
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