BISPECIFIC HETERODIMERIC DIABODIES AND USES THEREOF

이중특이성 이종이량체성 디아바디 분자 및 암의 치료에서의 이의 용도. 이중특이성 이종이량체성 디아바디 분자는 P-카데린 종양 세포 회합된 항원 및 CD3 T 세포 항원을 인식하는 2개의 에피토프 결합 자리를 형성하기 위해 회합하는 2개의 폴리펩티드 쇄를 포함한다. Bispecific heterodimeric diabody molecules and uses thereof in the treatment of cancer. The bispecific heterodimeric diabody molecules comprise two poly...

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Main Authors JOHNSON LESLIE S, ROOT ADAM REID, BLOOM LAIRD, BRADY WILLIAM A, MOSYAK LIDIA, MAY CHAD MICHAEL, TCHISTIAKOVA LIOUDMILA GENNADIEVNA, MOORE PAUL A
Format Patent
LanguageEnglish
Korean
Published 01.02.2017
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Abstract 이중특이성 이종이량체성 디아바디 분자 및 암의 치료에서의 이의 용도. 이중특이성 이종이량체성 디아바디 분자는 P-카데린 종양 세포 회합된 항원 및 CD3 T 세포 항원을 인식하는 2개의 에피토프 결합 자리를 형성하기 위해 회합하는 2개의 폴리펩티드 쇄를 포함한다. Bispecific heterodimeric diabody molecules and uses thereof in the treatment of cancer. The bispecific heterodimeric diabody molecules comprise two polypeptide chains that associate to form two epitope binding sites recognizing the P-cadherin tumor cell associated antigen and the CD3 T cell antigen.
AbstractList 이중특이성 이종이량체성 디아바디 분자 및 암의 치료에서의 이의 용도. 이중특이성 이종이량체성 디아바디 분자는 P-카데린 종양 세포 회합된 항원 및 CD3 T 세포 항원을 인식하는 2개의 에피토프 결합 자리를 형성하기 위해 회합하는 2개의 폴리펩티드 쇄를 포함한다. Bispecific heterodimeric diabody molecules and uses thereof in the treatment of cancer. The bispecific heterodimeric diabody molecules comprise two polypeptide chains that associate to form two epitope binding sites recognizing the P-cadherin tumor cell associated antigen and the CD3 T cell antigen.
Author TCHISTIAKOVA LIOUDMILA GENNADIEVNA
MAY CHAD MICHAEL
ROOT ADAM REID
MOORE PAUL A
MOSYAK LIDIA
JOHNSON LESLIE S
BLOOM LAIRD
BRADY WILLIAM A
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– fullname: MOORE PAUL A
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Snippet 이중특이성 이종이량체성 디아바디 분자 및 암의 치료에서의 이의 용도. 이중특이성 이종이량체성 디아바디 분자는 P-카데린 종양 세포 회합된 항원 및 CD3 T 세포 항원을 인식하는 2개의 에피토프 결합 자리를 형성하기 위해 회합하는 2개의 폴리펩티드 쇄를 포함한다. Bispecific...
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SubjectTerms CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
Title BISPECIFIC HETERODIMERIC DIABODIES AND USES THEREOF
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