TARP- 8 AMPA 6--3H-13--2- 6-SUBSTITUTED-3H-13-BENZOTHIAZOL-2-ONE COMPOUNDS AS TARP-GAMMA 8 DEPENDENT AMPA RECEPTOR ANTAGONISTS

• Main Authors: SPINAZZE PATRICK GIANPIETRO, REEL JON KEVIN, ORNSTEIN PAUL LESLIE, MAYHUGH DANIEL RAY, PORTER WARREN JAYE, STEVENS FREDDIE CRAIG, WITKIN JEFFREY MICHAEL, HOLLINSHEAD SEAN PATRICK, KHILEVICH ALBERT, SCHKERYANTZ JEFFREY MICHAEL, GERNERT DOUGLAS LINN, HAHN PATRIC JAMES, GARDINIER KEVIN MATTHEW
• Format: Patent
• Language: English; Korean
• Published: 09.12.2016
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

하기 화학식의 TARP γ8 의존성 AMPA 수용체 길항제; 그의 제약상 허용되는 염, 용도 및 그의 제조 방법이 기재되어 있다.여기서 X는 CH 또는 N이고; A는이고; R은 본원에 정의된 바와 같다. A TARP γ8 dependant AMPA receptor antagonist of the formula: wherein X is CH or N; A is and R1 is as defined herein; its pharmaceutically acceptable salts, uses, and methods for its prep...