HUMANIZATION OF RABBIT ANTIBODIES USING A UNIVERSAL ANTIBODY FRAMEWORK
본 발명은 보편적인 항체 수용체 프레임워크 및 비인간 항체, 예를 들면 래빗 항체를 보편적인 항체 수용체 프레임워크를 사용하여 그래프팅하는 방법에 관한 것이다. 본 발명의 방법에 의해 생산된 항체는 다양한 진단 및 치료 방법에 유용하다. The present invention relates to an universal antibody acceptor framework and to methods for grafting non-human antibodies, e.g., rabbit antibodies, using a universal...
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| Main Authors | , |
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| Format | Patent |
| Language | English Korean |
| Published |
15.07.2016
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| Subjects | |
| Online Access | Get full text |
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| Abstract | 본 발명은 보편적인 항체 수용체 프레임워크 및 비인간 항체, 예를 들면 래빗 항체를 보편적인 항체 수용체 프레임워크를 사용하여 그래프팅하는 방법에 관한 것이다. 본 발명의 방법에 의해 생산된 항체는 다양한 진단 및 치료 방법에 유용하다.
The present invention relates to an universal antibody acceptor framework and to methods for grafting non-human antibodies, e.g., rabbit antibodies, using a universal antibody acceptor framework. Antibodies generated by the methods of the invention are useful in a variety of diagnostic and therapeutic applications. |
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| AbstractList | 본 발명은 보편적인 항체 수용체 프레임워크 및 비인간 항체, 예를 들면 래빗 항체를 보편적인 항체 수용체 프레임워크를 사용하여 그래프팅하는 방법에 관한 것이다. 본 발명의 방법에 의해 생산된 항체는 다양한 진단 및 치료 방법에 유용하다.
The present invention relates to an universal antibody acceptor framework and to methods for grafting non-human antibodies, e.g., rabbit antibodies, using a universal antibody acceptor framework. Antibodies generated by the methods of the invention are useful in a variety of diagnostic and therapeutic applications. |
| Author | BORRAS LEONARDO URECH DAVID |
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| DocumentTitleAlternate | 보편적 항체 프레임워크를 사용한 래빗 항체의 인간화 |
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| Snippet | 본 발명은 보편적인 항체 수용체 프레임워크 및 비인간 항체, 예를 들면 래빗 항체를 보편적인 항체 수용체 프레임워크를 사용하여 그래프팅하는 방법에 관한 것이다. 본 발명의 방법에 의해 생산된 항체는 다양한 진단 및 치료 방법에 유용하다.
The present invention... |
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| Title | HUMANIZATION OF RABBIT ANTIBODIES USING A UNIVERSAL ANTIBODY FRAMEWORK |
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