FUSED HETEROARYL PYRIDYL AND PHENYL BENZENESUFLONAMIDES AS CCR2 MODULATORS FOR THE TREATMENT OF INFLAMMATION

CCR2 수용체의 강력한 길항물질로서 기능하는 화합물이 제시된다. 일반적으로, 이들 화합물은 아릴 술폰아마이드 유도체이고, CCR2 길항물질의 확인을 위한 검사에서 대조로서, CCR2-매개된 질환의 치료를 위한 제약학적 조성물과 방법에 유용하다. Compounds are provided that act as potent antagonists of the CCR2 receptor. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceuti...

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Main Authors PUNNA SREENIVAS, UNGASHE SOLOMON, WANG QIANG, ZENG YIBIN, KRASINSKI ANTONI
Format Patent
LanguageEnglish
Korean
Published 12.05.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract CCR2 수용체의 강력한 길항물질로서 기능하는 화합물이 제시된다. 일반적으로, 이들 화합물은 아릴 술폰아마이드 유도체이고, CCR2 길항물질의 확인을 위한 검사에서 대조로서, CCR2-매개된 질환의 치료를 위한 제약학적 조성물과 방법에 유용하다. Compounds are provided that act as potent antagonists of the CCR2 receptor. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases and as controls in assays for the identification of CCR2 antagonists.
AbstractList CCR2 수용체의 강력한 길항물질로서 기능하는 화합물이 제시된다. 일반적으로, 이들 화합물은 아릴 술폰아마이드 유도체이고, CCR2 길항물질의 확인을 위한 검사에서 대조로서, CCR2-매개된 질환의 치료를 위한 제약학적 조성물과 방법에 유용하다. Compounds are provided that act as potent antagonists of the CCR2 receptor. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases and as controls in assays for the identification of CCR2 antagonists.
Author PUNNA SREENIVAS
UNGASHE SOLOMON
ZENG YIBIN
WANG QIANG
KRASINSKI ANTONI
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DocumentTitleAlternate 염증의 치료를 위한 ＣＣＲ2 조절물질로서 융합된 헤테로아릴 피리딜과 페닐 벤젠술폰아마이드
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Snippet CCR2 수용체의 강력한 길항물질로서 기능하는 화합물이 제시된다. 일반적으로, 이들 화합물은 아릴 술폰아마이드 유도체이고, CCR2 길항물질의 확인을 위한 검사에서 대조로서, CCR2-매개된 질환의 치료를 위한 제약학적 조성물과 방법에 유용하다. Compounds are...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title FUSED HETEROARYL PYRIDYL AND PHENYL BENZENESUFLONAMIDES AS CCR2 MODULATORS FOR THE TREATMENT OF INFLAMMATION
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