TETRACYCLIC BROMODOMAIN INHIBITORS

본 발명은, 염증성 질환, 암, 및 AIDS를 포함하는 질환 및 상태의 치료에서 제제로서 유용한 화학식 I의 화합물 및 약제학적으로 허용되는 이의 염을 제공한다. 화학식 I상기 화학식 I에서, R, R, R, Y, Y, Y, A, A, A, 및 A는 명세서에서 정의된 값 중 어느 것을 갖는다. 또한 본 발명은, 하나 이상의 화학식 I의 화합물을 포함하는 약제학적 조성물을 제공한다. The present invention provides for compounds of formula (I)wherein R, R, R, Y, Y, Y,...

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Main Authors MARJANOVIC JASMINA, HASVOLD LISA A, MANTEI ROBERT A, HOLMS JAMES H, FIDANZE STEVEN D, WANG LE, DIETRICH JUSTIN D, SHEPPARD GEORGE S, DAI YUJIA, LIU DACHUN, MCDANIEL KEITH F, BOGDAN ANDREW, PRATT JOHN
Format Patent
LanguageEnglish
Korean
Published 10.11.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract 본 발명은, 염증성 질환, 암, 및 AIDS를 포함하는 질환 및 상태의 치료에서 제제로서 유용한 화학식 I의 화합물 및 약제학적으로 허용되는 이의 염을 제공한다. 화학식 I상기 화학식 I에서, R, R, R, Y, Y, Y, A, A, A, 및 A는 명세서에서 정의된 값 중 어느 것을 갖는다. 또한 본 발명은, 하나 이상의 화학식 I의 화합물을 포함하는 약제학적 조성물을 제공한다. The present invention provides for compounds of formula (I)wherein R, R, R, Y, Y, Y, A, A, A, and Ahave any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
AbstractList 본 발명은, 염증성 질환, 암, 및 AIDS를 포함하는 질환 및 상태의 치료에서 제제로서 유용한 화학식 I의 화합물 및 약제학적으로 허용되는 이의 염을 제공한다. 화학식 I상기 화학식 I에서, R, R, R, Y, Y, Y, A, A, A, 및 A는 명세서에서 정의된 값 중 어느 것을 갖는다. 또한 본 발명은, 하나 이상의 화학식 I의 화합물을 포함하는 약제학적 조성물을 제공한다. The present invention provides for compounds of formula (I)wherein R, R, R, Y, Y, Y, A, A, A, and Ahave any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
Author WANG LE
HOLMS JAMES H
FIDANZE STEVEN D
MANTEI ROBERT A
MCDANIEL KEITH F
SHEPPARD GEORGE S
BOGDAN ANDREW
LIU DACHUN
DIETRICH JUSTIN D
DAI YUJIA
MARJANOVIC JASMINA
HASVOLD LISA A
PRATT JOHN
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Snippet 본 발명은, 염증성 질환, 암, 및 AIDS를 포함하는 질환 및 상태의 치료에서 제제로서 유용한 화학식 I의 화합물 및 약제학적으로 허용되는 이의 염을 제공한다. 화학식 I상기 화학식 I에서, R, R, R, Y, Y, Y, A, A, A, 및 A는 명세서에서 정의된 값 중 어느 것을...
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HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title TETRACYCLIC BROMODOMAIN INHIBITORS
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