PYRAZINE CARBOXAMIDE COMPOUND

• Main Authors: TAKEMOTO YUKIHIRO, SHINDOU NOBUAKI, SAKAGAMI HIDEKI, MATSUYA TAKAHIRO, FUKUDOME HIROKI, HAMAGUCHI HISAO, KONDOH YUTAKA, KIKUCHI SHIGETOSHI, ONDA KENICHI, SHIMADA ITSURO, IIDA MAIKO
• Format: Patent
• Language: English; Korean
• Published: 26.09.2014
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

[Problem] A compound which is useful as an inhibitor on EGFR T790M mutation kinase activity is provided. [Means for Solution] The present inventors have investigated a compound having an inhibitory action on an EGFR T790M mutation kinase, and have found that a pyrazinecarboxamide compound has an inh...