PYRROLOTRIAZINONE DERIVATIVES AS PI3K INHIBITORS

• Main Authors: CATURLA JAVALOYES JUAN FRANCISCO, TERRICABRAS BELART EMMA, MATASSA VICTOR GIULIO, GRACIA FERRER JORDI, CARRASCAL RIERA MARTA, BERNAL ANCHUELA FRANCISCO JAVIER, TALTAVULL MOLL JOAN, ERRA SOLA MONTSERRAT
• Format: Patent
• Language: English; Korean
• Published: 20.02.2014
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

New pyrrolotriazinone derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks)