METHODS OF GENERATING NATURAL KILLER CELLS

Provided herein are in vitro two-step methods of producing populations of activated natural killer (NK) cells, comprising an expansion and a differentiation step. Also provided herein are populations of activated NK cells obtained by the method of the invention, and the use of the same in methods fo...

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Main Authors KANG LIN, ZEITLIN ANDREW, LAW ERIC, JASKO STEPHEN, ZHANG XIAOKUI, PAL AJAI, VOSKINARIAN BERSE VANESSA, HEIDARAN MOHAMMAD A, HARIRI ROBERT J, STOUT BHAVANI
Format Patent
LanguageEnglish
Korean
Published 21.08.2013
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Provided herein are in vitro two-step methods of producing populations of activated natural killer (NK) cells, comprising an expansion and a differentiation step. Also provided herein are populations of activated NK cells obtained by the method of the invention, and the use of the same in methods for treating cancer in an individual. Provided herein are also in vitro methods of suppressing the proliferation of tumor cells comprising contacting the tumor cells with a population of NK produced by the methods provided herein.
Bibliography:Application Number: KR20137003509