PHENYLIMIDAZOLE COMPOUNDS

• Main Authors: SHIBUTANI TADAO, IWATA KOUSHI, KIDO SATOSHI
• Format: Patent
• Language: English; Korean
• Published: 10.10.2011
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

[Object] To provide a pharmaceutical product (chemotherapeutic agent) effective in the prevention and treatment of hyperlipidemia, obesity, etc. [Solving Means] A phenylimidazole compound represented by the following General Formula (1): wherein, R 1 represents a hydrogen atom, a phenyl lower alkyl group optionally having a substituent, or a pyridyl lower alkyl group optionally having a substituent, and the benzene ring and the pyridine ring are optionally substituted with 1 or 2 substituents selected from the group consisting of halogen atoms, cyano group and halogen-substituted lower alkyl groups. One of R 2 and R 3 represents a hydrogen atom and the other represents a lower alkoxy group. R 4 represents a phenyl group optionally having a substituent. R 5 and R 6 are the same or different, and represent a hydrogen atom or a lower alkyl group. R 7 and R 8 are the same or different, and represent a hydrogen atom or a lower alkoxy group. However, when R 1 represents an unsubstituted phenyl lower alkyl group, R 2 represents a lower alkoxy group, R 3 represents a hydrogen atom, R 4 represents a phenyl group optionally having a substituent, and R 5 represents a hydrogen atom, R 6 is not a hydrogen atom.