PYRIMIDINE DERIVATIVES USEFUL AS RAF KINASE INHIBITORS

• Main Authors: JONES JOHN HOWARD, TANAKA HIROKO, POWELL NOEL, RAIMUNDO BRIAN, WYNN THOMAS, GUAN BING, XIN ZHILI, COSSROW JENNIFER, FRANKLIN LIOYD, LUGOVSKOY ALEXEY, KUMARAVEL GNANASAMBANDAM, LANE BENJAMIN, CHEN WEIRONG, PENG HAIRUO, VESSELS JEFFREY, LITTKE ADAM
• Format: Patent
• Language: English; Korean
• Published: 29.03.2010
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention provides compounds useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf-mediated diseases.