PYRIDAZIN-3(2H)-ONE DERIVATIVES AND THEIR USE AS PDE4 INHIBITORS

• Main Authors: PAGES SANTACANA LLUIS MIQUEL, BUIL ALBERO MARIA ANTONIA, GRACIA FERRER JORDI, GARRIDO RUBIO YOLANDA, DAL PIAZ VITTORIO, TALTAVULL MOLL JOAN
• Format: Patent
• Language: English
• Published: 14.03.2007
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

The invention relates to new therapeutically useful pyridazin-3(2H)-one derivatives of Formula (I) and to pharmaceutical compositions containing them. These compounds are potent and selective inhibitors of phosphodiesterase 4 (PDE4) and are thus useful in the treatment, prevention or suppression of...