Novel Processes and Intermediates

• Main Authors: DEVRIES KEITH MICHAEL, HOOVER DENNIS JAY, HANMEN PHILIP DIETRICH, JORGENSEN JEFFERY BRIAN, FOX DARRELL EUGENE
• Format: Patent
• Language: English; Korean
• Published: 15.06.2001
• Edition: 7
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; APPARATUS THEREFOR; CHEMISTRY; GENERAL METHODS OF ORGANIC CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

PURPOSE: Provided is a novel manufacturing method of 3(S)-((5-chloro-1H-indole-2-carbonyl)- amino)-2(R)-hydroxy-4-phenyl-butyric acid at a low cost by reacting two specific kinds of compounds and extracting with an organic solvent, thereby producing indole-2-carboxamide and its derivative which have...