IL10RA Composition for diagnosing of refractory inflammatory bowel disease in pediatric patients comprising single nucleotide polymorphism marker in IL10RA gene

• Main Authors: OH, SEAK HEE, KIM, KYUNG MO, BAEK, JI WON, SONG, KYU YOUNG
• Format: Patent
• Language: English; Korean
• Published: 08.12.2016
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; VINEGAR; WINE

The present invention relates to a child intractable inflammatory bowel disease diagnosing composition including a single nucleotide polymorphism marker in an IL10RA gene. Specifically, a mutation (T179T) which does not induce a change in amino acids in IL10RA known as a gene of a child intractable...