SUBSTITUTED PYRIMIDINE DERIVATIVES, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF AS REAGENTS

• Main Authors: LANG, HANS-YOCHEN, GEISEN, KARL, NIMMESGERN, HILDEGARD, UTZ, ROLAND
• Format: Patent
• Language: English; Korean
• Published: 15.06.1999
• Edition: 6
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

하기 일반식(I)의 피리미딘 유도체, 이의 염 및 이를 제조하는 방법이 기술되어 있다. 상기 식에서, R, R, X 및 Y는 명세서에서 정의한 바와 같다. 이들의 소르비톨-축적 활성 때문에, 이들은 알도스 리덕타제 억제제 시험용으로 유리한 약물학적 스크리닝 모델을 위한 약제로서 사용하기에 적합하다. Pyrimidine derivatives of the formula I I in which R1, R2, X and Y have the stated meaning, the salts thereof and a process for the...