4-HYDROXYTETRAHYDROPYRAN-2-ONES AND THE CORRESPONDING DEHYDROXY CARBOXYLIC ACID DERIVATIVES, SALTS AND ESTERS AND A PROCESS FOR THEIR PREPARATION AS WELL AS PRECURSORS

본 발명은 4-하이드록시테트라하이드라피란-2-온 및 상응하는 디하이드록시카복실 산 유도체, 염 및 에스테르, 이의 제조방법, 약제로서 이의 용도, 및 약제학적 제제 및 전구체에 관한 것으로, 본 발명에 따르는 신규 화합물은 동맥경화증 및 과콜레스테린 혈증의 예방 및 치료에 유용하다. Compounds of the formula I and the corresponding open-chain dihydroxy carboxylic acids of the formula II in which X, Y, R , R , R , R , R hav...

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Main Authors WESS, GUENTHER, JENDRALLA, HEINER, BECK. GERHARD, KESSELER, KURT
Format Patent
LanguageEnglish
Korean
Published 01.12.1998
Edition6
Subjects
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Abstract 본 발명은 4-하이드록시테트라하이드라피란-2-온 및 상응하는 디하이드록시카복실 산 유도체, 염 및 에스테르, 이의 제조방법, 약제로서 이의 용도, 및 약제학적 제제 및 전구체에 관한 것으로, 본 발명에 따르는 신규 화합물은 동맥경화증 및 과콜레스테린 혈증의 예방 및 치료에 유용하다. Compounds of the formula I and the corresponding open-chain dihydroxy carboxylic acids of the formula II in which X, Y, R , R , R , R , R have the stated meanings, and their pharmacologically acceptable salts with bases and their pharmacologically acceptable esters, process for the preparation of these compounds, their use as drugs, and pharmaceutical preparations are described. Also described are compounds of the formula III in which R , R , R , R , R , X and Y have the stated meanings.
AbstractList 본 발명은 4-하이드록시테트라하이드라피란-2-온 및 상응하는 디하이드록시카복실 산 유도체, 염 및 에스테르, 이의 제조방법, 약제로서 이의 용도, 및 약제학적 제제 및 전구체에 관한 것으로, 본 발명에 따르는 신규 화합물은 동맥경화증 및 과콜레스테린 혈증의 예방 및 치료에 유용하다. Compounds of the formula I and the corresponding open-chain dihydroxy carboxylic acids of the formula II in which X, Y, R , R , R , R , R have the stated meanings, and their pharmacologically acceptable salts with bases and their pharmacologically acceptable esters, process for the preparation of these compounds, their use as drugs, and pharmaceutical preparations are described. Also described are compounds of the formula III in which R , R , R , R , R , X and Y have the stated meanings.
Author BECK. GERHARD
WESS, GUENTHER
JENDRALLA, HEINER
KESSELER, KURT
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Snippet 본 발명은 4-하이드록시테트라하이드라피란-2-온 및 상응하는 디하이드록시카복실 산 유도체, 염 및 에스테르, 이의 제조방법, 약제로서 이의 용도, 및 약제학적 제제 및 전구체에 관한 것으로, 본 발명에 따르는 신규 화합물은 동맥경화증 및 과콜레스테린 혈증의 예방 및 치료에 유용하다....
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SubjectTerms ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title 4-HYDROXYTETRAHYDROPYRAN-2-ONES AND THE CORRESPONDING DEHYDROXY CARBOXYLIC ACID DERIVATIVES, SALTS AND ESTERS AND A PROCESS FOR THEIR PREPARATION AS WELL AS PRECURSORS
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