STEROID-5-Ñß-REDUCTASE INHIBITORS

• Main Authors: ALAN, HOLT DENNIS, LEVY, MARK ALAN, TICKNER, ANN MARIE, KOWALSKI, CONRAD JOHN, METCALF, BRIAN WALTER
• Format: Patent
• Language: English; Korean
• Published: 11.04.1998
• Edition: 6
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; STEROIDS; VINEGAR; WINE

Compounds of formula (I) : in which, inter alia, R is H or C1-8alkyl and M is O or S, processes for their preparation, pharmaceutical compositions containing then and their use as inhibitors of 5- alpha -reductase in the treatment in the reduction of prostate size.