MONOCLONAL ANTIBODY AGAINST NON-STRUCTURAL REGION NS3 OF NON-A, NON-B TYPE HEPATITIS VIRUS, HYBRIDOMA PRODUCING THE SAME, AND MEASUREMENT AND PURIFICATION OF THE VIRUS ANTIGEN WITH THE MONOCLONAL ANTIBODY

• Main Authors: OTA YOSUKE, KASHIWAGUMA TOMIKO, SUGI MASATO, YAMAMOTO TAKAYUKI, MORI HIROYUKI
• Format: Patent
• Language: English
• Published: 21.06.1994
• Edition: 5
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROCESSES USING MICROORGANISMS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; TESTING; VINEGAR; WINE

PURPOSE:To obtain the subject antibody capable of detecting and determining a viral antigen in high sensitivity, accuracy and specificity and of being effectively used for the purification of the viral antigen. CONSTITUTION:This monoclonal antibody specifically binding to an epitope on the polypeptide antigen in the non-structural region NS3 of a non-A, non-B type hepatitis virus, a hybridoma producing the monoclonal antibody, and the method for measuring and purifying the viral antibody with the monoclonal antibody.