TIGHT JUNCTION FORMATION PROMOTER, EPITHELIAL BARRIER FUNCTION IMPROVER, AND PHARMACEUTICAL, QUASI DRUG, FOOD AND DRINK, AND COSMETIC

• Main Authors: HATA TOMONORI, ODA HIROE, HASHII YOKO, ATSUGI TORU, SHU ENYO, KAWASHIMA YOSHIHITO
• Format: Patent
• Language: English; Japanese
• Published: 09.08.2023
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

To provide a novel technique for promoting the formation of a tight junction.SOLUTION: The present invention relates to a tight junction formation promoter and an epithelial barrier function improver, each comprising at least one substance selected from Magnolia champaca (Michelia champaca) extract, acteoside, and isoacteoside as an active ingredient. The tight junction formation promoter and the epithelial barrier function improver according to the present technique can be used in pharmaceuticals, topical skin preparations, foods, quasi drugs and cosmetics.SELECTED DRAWING: Figure 1 【課題】タイトジャンクションの形成を促進するための新規な技術を提供すること。【解決手段】キンコウボク（Magnolia champaca （Michelia champaca））の抽出物、アクテオシド、およびイソアクテオシドから選択される１以上の物質を有効成分とする、タイトジャンクション形成促進剤、および上皮バリア機能改善剤を提供する。本技術に係るタイトジャンクション形成促進剤、および上皮バリア機能改善剤は、医薬品、皮膚外用剤、食品、医薬部外品および化粧料に用いることができる。【選択図】図１