AQUEOUS ORAL CARE FLUORIDE TREATMENT COMPOSITIONS, AND METHODS

• Main Authors: WANG YIZHONG, MELINDA B GUSTAFSON, CAROLA A CARRERA VIDAL, PAUL R KLAIBER, OXMAN JOEL D, TIFFANY T TON, JENNIFER POST
• Format: Patent
• Language: English; Japanese
• Published: 11.07.2023
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS

To provide compositions that are simply applied to teeth as varnishes and work in a short time like gel/foam formulations, and methods for treatment.SOLUTION: An aqueous oral care fluoride treatment composition is disclosed, wherein the composition includes: 0.1 wt.% to 3.0 wt.% of a crosslinked poly acid having carboxylic acid side groups; a pharmaceutically acceptable buffer; 1.0 wt.% to 2.5 wt.% of sodium fluoride; 0.025 wt.% to 1.75 wt.% of a multivalent cation salt; and at least 60 wt.% water; wherein the weight percentages are based on the total weight of the aqueous composition. Also disclosed are a method of providing fluoride to a patient's tooth surface, and a method of reducing the incidence of dental caries.SELECTED DRAWING: None 【課題】ワニスとして歯に適用するのが簡単であり、ゲル／発泡体製剤と同様に短い期間で作用する組成物、及び処置する方法を提供する。【解決手段】水性口腔ケアフッ化物処置組成物であって、０．１重量％～３．０重量％の、カルボン酸側基を有する架橋ポリ酸と、薬学的に許容される緩衝剤と、１．０重量％～２．５重量％のフッ化ナトリウムと、０．０２５重量％～１．７５重量％の多価カチオン塩と、少なくとも６０重量％の水とを含み、ここで、重量％は水性組成物の総重量に基づくものである、処置組成物、フッ化物を患者の歯表面に付与する方法、及びう歯の発生率を低減する方法が開示される。【選択図】なし