INTESTINAL FLORA IMPROVING AGENT

• Main Authors: OISHI HIFUMI, HATTORI TAKASHI, TANI HISANORI
• Format: Patent
• Language: English; Japanese
• Published: 31.03.2022
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

To provide an intestinal enterobacterial flora improving agent and an innate immunity activating agent that are for use in suppressing the growth of Escherichia coli in intestinal flora and promoting the growth of Akkermansia, bifido, and lactic acid bacteria.SOLUTION: Provided are an intestinal flora improving agent and an innate immunity activating agent, which are an intestinal flora improving agent and an innate immunity activating agent containing glucosaminoglycan including hyaluronic acid, heparan sulfate, and chondroitin sulfate A, and in which, preferably, hyaluronic acid is contained in an amount of 10 to 150 μg/mg, heparan sulfate is contained in an amount of 200 to 400 μg/mg, and chondroitin sulfate A is contained in an amount of 50 to 150 μg/mg with respect to the total.SELECTED DRAWING: Figure 1 【課題】腸内フローラの大腸菌の増殖抑制およびアッカーマンシア菌、ビフィズス菌、および乳酸菌の増殖促進に使用するための腸内細菌叢フローラ改善剤及び自然免疫賦活化剤を提供する。【解決手段】ヒアルロン酸、ヘパラン硫酸、およびコンドロイチン硫酸Ａを含むグルコサミノグリカンを含む腸内フローラ改善剤及び自然免疫賦活化剤であって、好ましくは、全体に対して、ヒアルロン酸が１０～１５０μｇ／ｍｇの量、ヘパラン硫酸が２００～４００μｇ／ｍｇの量、コンドロイチン硫酸Ａが５０～１５０μｇ／ｍｇの量で含まれる、前記腸内フローラ改善剤及び自然免疫賦活化剤を提供する。【選択図】図１