HIGH CONVECTION HOME HEMODIALYSIS/HEMOFILTRATION AND SORBENT SYSTEM

• Main Authors: EL SAYYID WALEED MUTASEM, CHILDERS ROBERT W, ROGER RODOLFO, KELLY THOMAS D, DIN SHAHID Q, BUSBY DON
• Format: Patent
• Language: English; Japanese
• Published: 18.07.2019
• Subjects: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; SEPARATION; TRANSPORTING

To provide a system, method, and apparatus for performing a renal replacement therapy.SOLUTION: In one embodiment, two small high flux dialyzers (20, 30) are connected in series. Restriction means (40) is placed between the two dialyzers in the dialysate flow path (962). The restriction means is variable and adjustable in one preferred embodiment. The restriction means builds a positive pressure in the venous dialyzer, causing a high degree of intentional backfiltration. That backfiltration causes a significant flow of dialysate through the high flux venous membrane directly into the patient's blood. That backfiltered solution is subsequently ultrafiltered from the patient through the arterial dialyzer. The diffusion of dialysate into the venous filter and removal of dialysate from the arterial dialyzer cause a convective transport of toxins from the patient. Additionally, the dialysate that does not diffuse directly into the patient but instead flows across the membranes of both dialyzers provides a diffusive clearance of waste products.SELECTED DRAWING: Figure 1 【課題】腎置換療法を行うためのシステム、方法および装置を提供すること。【解決手段】一実施形態では、２つの小型高流量透析装置（２０、３０）が直列に接続される。制限手段（４０）は、透析液流路（９６２）内の２つの透析装置間に配置される。制限手段は、１つの好ましい実施形態において可変および調節可能である。制限手段は、静脈透析装置内に正圧を形成し、高度の意図的な逆濾過を生じる。この逆濾過によって、高流量静脈膜を通る透析液の著しい流れは、患者の血液中に直接入る。逆濾過された溶液は、その後、動脈透析装置を通して患者から限外濾過される。静脈濾過器内に透析液を拡散させ、動脈透析装置から透析液を除去することによって、患者からの毒素が対流搬送される。さらに、患者の体内に直接拡散せず、代わりに両方の透析装置の膜を横断して流れる透析液は、老廃物の拡散浄化を提供する。【選択図】図１