LEVODOPA-CONTAINING COMPACT TABLET HAVING EXCELLENT SUSTAINED-RELEASE PROPERTIES

To provide a sustained-release tablet having excellent sustained-release properties, having improved convenience, and containing levodopa and carbidopa.SOLUTION: A compact sustained-release tablet contains a medicine that is levodopa, or ester or salt thereof, and has a weight of 10.0-40.0 mg per pr...

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Bibliographic Details
Main Authors TANIGUCHI TOSHIYA, GOCHOMORI KAZUHIRO
Format Patent
LanguageEnglish
Japanese
Published 07.03.2019
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide a sustained-release tablet having excellent sustained-release properties, having improved convenience, and containing levodopa and carbidopa.SOLUTION: A compact sustained-release tablet contains a medicine that is levodopa, or ester or salt thereof, and has a weight of 10.0-40.0 mg per preparation. Desirably, the sustained-release tablet further contains a medicine that is carbidopa or benserazide, and contains a granule containing the medicine, and contains a polymer selected from a water-soluble polymer, water-insoluble polymer and enteric-coated polymer.SELECTED DRAWING: None 【課題】良好な徐放性を有し、利便性が向上した、レボドパ及びカルビドパを含有する徐放錠剤を提供すること。【解決手段】レボドパ若しくは其のエステル又は其の塩である薬物を含有し、１製剤単位あたりの重量が１０．０〜４０．０ｍｇである小型化された徐放錠。望ましくはカルビドパ又はベンセラジドである薬物を更に含有し、薬物を含む造粒物を含有し、水溶性高分子、水不溶性高分子及び腸溶性高分子から選ばれる高分子ポリマーを含有している。【選択図】なし
Bibliography:Application Number: JP20170158276