REMOVAL OF MICROORGANISM FROM CELL CULTURE MEDIUM

• Main Authors: PHILIP M GODDARD, PETERS ANTONI
• Format: Patent
• Language: English; Japanese
• Published: 30.06.2016
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SEPARATION; SPIRITS; TRANSPORTING; VINEGAR; WINE

PROBLEM TO BE SOLVED: To provide: a composition for removing viral impurities from a chemically-regulated cell culture medium; a porous membrane to which the composition is applied; and an impurity removal method by the membrane.SOLUTION: In a production method of an asymmetrical porous membrane having a surface modified with a diacetone acrylamide monomer crosslinked and arrayed at random, a composition is a polymer containing a diacetone acrylamide monomer and one or more kinds of a non-acrylamide crosslinkable monomer. A removal method of impurities by using the membrane is also provided.SELECTED DRAWING: None 【課題】化学的に規定された細胞培養培地からウイルス性夾雑物を除去するための組成物とそれを適用した多孔性膜及び該膜による該夾雑物除去方法の提供。【解決手段】該組成物はジアセトンアクリルアミドモノマーと１種以上の非アクリルアミド架橋性モノマーとを含むポリマーであって、ランダムに配列され、架橋された該ジアセトンアクリルアミドモノマーによって修飾された表面を有する非対称性多孔性膜の製造方法、及び該膜を使用しての該夾雑物の除去方法を提供する。【選択図】なし