ISOINDOLINE COMPOUNDS FOR USE IN TREATMENT OF CANCER

• Main Authors: GEORGE W MULLER, ALEXANDER L RUCHELMAN
• Format: Patent
• Language: English; Japanese
• Published: 17.12.2015
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

PROBLEM TO BE SOLVED: To provide novel isoindoline compounds, and pharmaceutical compositions comprising the compounds.SOLUTION: The present invention provides compounds represented by formula (V), pharmaceutical compositions comprising the compounds, and the use of the compounds in production of the pharmaceutical compositions for treating, preventing or managing various diseases or disorders. (X is C(=O) or CH; m is an integer from 0 to 3; and Rand Rare each independently H, halogen, Calkyl, or Caryloxy.) 【課題】新規イソインドリン化合物、及び該化合物を含む医薬組成物の提供。【解決手段】式（Ｖ）で表される化合物、前記化合物を含む医薬組成物、及び様々な疾患又は障害を治療、予防又は管理する為の医薬組成物製造における前記化合物の使用。（ＸはＣ（＝Ｏ）文は、ＣＨ２；ｍは０〜３の整数；Ｒ１０及びＲ１１は各々独立にＨ、ハロゲン、Ｃ１−６アルキル、Ｃ６−１０のアリールオキシ）【選択図】なし