TREATMENT OF α-GALACTOSIDASE A DEFICIENCY

• Main Authors: WILLIAMS MELANIE D, SCHUETZ THOMAS J, KINOSHITA CAROL M, DANIEL PETER F, SELDEN RICHARD F, TRECO DOUGLAS A, BOROWSKI MARIANNE
• Format: Patent
• Language: English; Japanese
• Published: 14.05.2015
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

PROBLEM TO BE SOLVED: To provide a highly refined α-Gal A and various refining methods for the same, to provide an α-Gal A preparation having altered electric charges and a method for producing the same, to provide an α-Gal A preparation having circulatory half-life extended in a mammalian host and...