5-HETEROARYL SUBSTITUTED INDAZOLES AS KINASE INHIBITORS
PROBLEM TO BE SOLVED: To provide compounds which inhibit specific combinations of kinases or target kinase pathways.SOLUTION: The present invention relates to 5-substituted indazole compounds represented by the specified general formula (I) or pharmaceutically acceptable salts of the compounds. The...
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Main Authors | , , , , , , , , , , , , , , , , , , , , , , , |
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Format | Patent |
Language | English |
Published |
24.04.2014
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Subjects | |
Online Access | Get full text |
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Summary: | PROBLEM TO BE SOLVED: To provide compounds which inhibit specific combinations of kinases or target kinase pathways.SOLUTION: The present invention relates to 5-substituted indazole compounds represented by the specified general formula (I) or pharmaceutically acceptable salts of the compounds. The present invention relates also to methods of making the compounds, and to compositions containing the compounds useful for inhibiting kinases such as Glycogen Synthase kinase 3 (GSK-3), Rho kinase (ROCK), Janus Kinases (JAK), AKT, PAK4, PLK, CK2, KDR, MK2, JNK1, aurora, pim1 and nek2. |
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Bibliography: | Application Number: JP20130266989 |