BIOLOGICAL PREPARATION

PROBLEM TO BE SOLVED: To provide antibody molecules for treating NHL, capable of being repeatedly used and easily and efficiently produced.SOLUTION: An antibody containing at least one CDR obtained from a mouse monoclonal antibody having specificity to CD22 is disclosed. A CDR transplanted antibody,...

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Bibliographic Details
Main Authors POPPLEWELL ANDREW GEORGE, LADYMAN HEATHER MARGARET, TICKLE SIMON PETER
Format Patent
LanguageEnglish
Published 14.11.2013
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:PROBLEM TO BE SOLVED: To provide antibody molecules for treating NHL, capable of being repeatedly used and easily and efficiently produced.SOLUTION: An antibody containing at least one CDR obtained from a mouse monoclonal antibody having specificity to CD22 is disclosed. A CDR transplanted antibody, wherein at least one CDR is a modified CDR, is also disclosed. Furthermore, a DNA sequence encoding chains of antibody molecules, a vector, transformed host cells and use of the antibody molecules in the treatment of diseases mediated with CD22 expressing cells are disclosed.
Bibliography:Application Number: JP20130140245