TRANS-9,10-DEHYDROEPOTHILONE C AND D, ANALOG THEREOF AND METHOD OF MAKING THE SAME

PROBLEM TO BE SOLVED: To inhibit cellular hyperproliferation and/or stabilize microtubules in vitro and treat hyperproliferative diseases in vivo.SOLUTION: The present invention provides new trans-9,10-dehydroepothilone C and trans-9,10-dehydroepothilone D based derivative compounds, compositions an...

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Main Authors SUNDERMANN KURT, TANG LI, LI YONG, MYLES DAVID
Format Patent
LanguageEnglish
Published 17.10.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract PROBLEM TO BE SOLVED: To inhibit cellular hyperproliferation and/or stabilize microtubules in vitro and treat hyperproliferative diseases in vivo.SOLUTION: The present invention provides new trans-9,10-dehydroepothilone C and trans-9,10-dehydroepothilone D based derivative compounds, compositions and methods. Also disclosed are methods of making the compounds.
AbstractList PROBLEM TO BE SOLVED: To inhibit cellular hyperproliferation and/or stabilize microtubules in vitro and treat hyperproliferative diseases in vivo.SOLUTION: The present invention provides new trans-9,10-dehydroepothilone C and trans-9,10-dehydroepothilone D based derivative compounds, compositions and methods. Also disclosed are methods of making the compounds.
Author MYLES DAVID
LI YONG
TANG LI
SUNDERMANN KURT
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Snippet PROBLEM TO BE SOLVED: To inhibit cellular hyperproliferation and/or stabilize microtubules in vitro and treat hyperproliferative diseases in vivo.SOLUTION: The...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title TRANS-9,10-DEHYDROEPOTHILONE C AND D, ANALOG THEREOF AND METHOD OF MAKING THE SAME
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