CONTROLLED RELEASE NANOPARTICLE COMPOSITION

PROBLEM TO BE SOLVED: To provide a controlled release nanoparticle composition comprising a nanoparticulate agonist to be administered, and a rate-controlling polymer which functions to prolong the release of the agonist following administration.SOLUTION: The composition is a controlled release nano...

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Bibliographic Details
Main Authors CLANCY MAURICE JOSEPH ANTHONY, JAIN RAJEEV A, CODD JANET ELIZABETH, HONTZ ROBERT, CUMMING KENNETH IAIN, DEVANE JOHN G, SWANSON JON
Format Patent
LanguageEnglish
Published 23.05.2013
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To provide a controlled release nanoparticle composition comprising a nanoparticulate agonist to be administered, and a rate-controlling polymer which functions to prolong the release of the agonist following administration.SOLUTION: The composition is a controlled release nanoparticle composition comprising: (a) a slightly soluble agonist which can be administrated and has an effective average particle size of less than about 1,000 nm; (b) at least one surface stabilizer associating with the surface of the agonist; and (c) at least one pharmaceutically acceptable rate-controlling polymer, wherein the composition provides controlled release of the agonist following administration for a time period ranging from about 2 to about 24 hours or longer.
Bibliography:Application Number: JP20130032704