UREA DERIVATIVE AND MEDICAL USE THEREOF

PROBLEM TO BE SOLVED: To provide a compound having a new working mechanism which is effective to treatment of NASH, and to provide a medical use thereof.SOLUTION: This invention relates to an urea derivative represented by general formula (I) or its pharmacologically acceptable salt. [In the formula...

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Main Authors AOKI TAKUMI, SHIMOZONO RIEKO, YOSHIZAWA YOSHITAKA, NODA HIDETOSHI, MORITA YASUHIRO
Format Patent
LanguageEnglish
Published 29.11.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract PROBLEM TO BE SOLVED: To provide a compound having a new working mechanism which is effective to treatment of NASH, and to provide a medical use thereof.SOLUTION: This invention relates to an urea derivative represented by general formula (I) or its pharmacologically acceptable salt. [In the formula, A is a substituent represented by general formula (IIa) or (IIb), and R is a hydrogen atom, a halogen atom, 1-4C alkoxy, or 6-12 aryloxy which may have a substituent]. (In the general formula (IIb), R is a hydrogen atom, a halogen atom, 1-4C alkoxy, or 6-12 aryloxy which may have a substituent).
AbstractList PROBLEM TO BE SOLVED: To provide a compound having a new working mechanism which is effective to treatment of NASH, and to provide a medical use thereof.SOLUTION: This invention relates to an urea derivative represented by general formula (I) or its pharmacologically acceptable salt. [In the formula, A is a substituent represented by general formula (IIa) or (IIb), and R is a hydrogen atom, a halogen atom, 1-4C alkoxy, or 6-12 aryloxy which may have a substituent]. (In the general formula (IIb), R is a hydrogen atom, a halogen atom, 1-4C alkoxy, or 6-12 aryloxy which may have a substituent).
Author NODA HIDETOSHI
AOKI TAKUMI
SHIMOZONO RIEKO
MORITA YASUHIRO
YOSHIZAWA YOSHITAKA
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Snippet PROBLEM TO BE SOLVED: To provide a compound having a new working mechanism which is effective to treatment of NASH, and to provide a medical use...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title UREA DERIVATIVE AND MEDICAL USE THEREOF
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