STABILIZED INTERFERON COMPOSITION
PROBLEM TO BE SOLVED: To provide a protein pharmacological composition (comprising an IFN-β composition). SOLUTION: A stabilized pharmaceutical formulations comprising the IFN-β and highly purified mannitol are provided. The highly purified mannitol stabilizes the compositions by reducing the format...
Saved in:
| Main Authors | , |
|---|---|
| Format | Patent |
| Language | English |
| Published |
27.03.2008
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | PROBLEM TO BE SOLVED: To provide a protein pharmacological composition (comprising an IFN-β composition). SOLUTION: A stabilized pharmaceutical formulations comprising the IFN-β and highly purified mannitol are provided. The highly purified mannitol stabilizes the compositions by reducing the formation of IFN-β adducts in comparison with IFN-β formulated with mannitol that has not been highly purified. Methods for increasing the stability of IFN-β or a variant thereof in a liquid or lyophilized composition and for increasing storage stability of such a composition are also provided. COPYRIGHT: (C)2008,JPO&INPIT |
|---|---|
| AbstractList | PROBLEM TO BE SOLVED: To provide a protein pharmacological composition (comprising an IFN-β composition). SOLUTION: A stabilized pharmaceutical formulations comprising the IFN-β and highly purified mannitol are provided. The highly purified mannitol stabilizes the compositions by reducing the formation of IFN-β adducts in comparison with IFN-β formulated with mannitol that has not been highly purified. Methods for increasing the stability of IFN-β or a variant thereof in a liquid or lyophilized composition and for increasing storage stability of such a composition are also provided. COPYRIGHT: (C)2008,JPO&INPIT |
| Author | WOLFE SIDNEY N HORA MANINDER S |
| Author_xml | – fullname: HORA MANINDER S – fullname: WOLFE SIDNEY N |
| BookMark | eNrjYmDJy89L5WRQDA5xdPL08YxydVHw9AtxDXJzDfL3U3D29w3wD_YM8fT342FgTUvMKU7lhdLcDEpuriHOHrqpBfnxqcUFicmpeakl8V4BRgYGFgZmlobmho7GRCkCAF7NJLk |
| ContentType | Patent |
| DBID | EVB |
| DatabaseName | esp@cenet |
| DatabaseTitleList | |
| Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Chemistry Sciences |
| ExternalDocumentID | JP2008069171A |
| GroupedDBID | EVB |
| ID | FETCH-epo_espacenet_JP2008069171A3 |
| IEDL.DBID | EVB |
| IngestDate | Fri Jul 19 13:11:13 EDT 2024 |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | false |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-epo_espacenet_JP2008069171A3 |
| Notes | Application Number: JP20070278231 |
| OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20080327&DB=EPODOC&CC=JP&NR=2008069171A |
| ParticipantIDs | epo_espacenet_JP2008069171A |
| PublicationCentury | 2000 |
| PublicationDate | 20080327 |
| PublicationDateYYYYMMDD | 2008-03-27 |
| PublicationDate_xml | – month: 03 year: 2008 text: 20080327 day: 27 |
| PublicationDecade | 2000 |
| PublicationYear | 2008 |
| RelatedCompanies | CHIRON CORP |
| RelatedCompanies_xml | – name: CHIRON CORP |
| Score | 2.6970253 |
| Snippet | PROBLEM TO BE SOLVED: To provide a protein pharmacological composition (comprising an IFN-β composition). SOLUTION: A stabilized pharmaceutical formulations... |
| SourceID | epo |
| SourceType | Open Access Repository |
| SubjectTerms | DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| Title | STABILIZED INTERFERON COMPOSITION |
| URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20080327&DB=EPODOC&locale=&CC=JP&NR=2008069171A |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LS8NAEB5qFfWmVVGrEkVyC-ZlHocgzYsmmAdtlOKlZDdbEKEWG_HvO9k22lNvyw7M7g7MzH6zM7MA91RXKCVUlSiaSEkviSWVlUYko7RVmWikNHkcMkmN4YseTx4nHfhoa2F4n9Af3hwRNYqivtfcXi_-g1g-z61cPpB3nPp8CgvHF1t0bMmaaoq-6wR55mee6HlOnIvpaEUzEJsogx3YxXu02ahD8Oo2ZSmLTZ8SHsFejuzm9TF02LwHB1779VoP9pP1izcO18q3PIHbcTFwo-foLfAF3sk2DEZZKnhZkmfjqAk1ncJdGBTeUMK1pn8nm8b5xr60M-gi5GfnIFgzW6YVUxWGgMGYVURVUHilbSiMMWpYF9DfwuhyK7UPh6ucB01SzSvo1l_f7Boda01uuEB-AYGGeRA |
| link.rule.ids | 230,309,783,888,25576,76876 |
| linkProvider | European Patent Office |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LS8NAEB5qFetNq6LWRxTJLdg8zOMQpM2DpOZFG6V4KdntFkSoxUb8-062jfbU27IDs7sDM7Pf7MwswD3VZEoJVSSKJlLSCmJKxVQlkl5YSpeopDB4HDJO9OBFG4wfxw34qGtheJ_QH94cETWKor6X3F4v_oNYLs-tXD6Qd5z6fPJz2xVrdGx2VcUQ3b7tZambOqLj2INMTIYrmo7YRO7twC7esY1KHbzXflWWstj0Kf4h7GXIbl4eQYPN29By6q_X2rAfr1-8cbhWvuUx3I7yXj-MwjfPFXgnW98bpongpHGWjsIq1HQCd76XO4GEa03-TjYZZBv7Uk-hiZCfnYFgzqwunTJFZggY9NmUKDIKr7B0mTFGdfMcOlsYXWyl3kAryONoEoXJcwcOVvkPqqQYl9Asv77ZFTrZklxz4fwCWX98Aw |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=STABILIZED+INTERFERON+COMPOSITION&rft.inventor=HORA+MANINDER+S&rft.inventor=WOLFE+SIDNEY+N&rft.date=2008-03-27&rft.externalDBID=A&rft.externalDocID=JP2008069171A |