USE OF PROSTAGLANDIN (PGE2) RECEPTOR 4 (EP4) SELECTIVE AGONIST FOR TREATMENT OF ACUTE AND CHRONIC RENAL FAILURE

• Main Authors: PARALKAR VISHWAS MADHAV, THOMPSON DAVID DUANE
• Format: Patent
• Language: English
• Published: 13.07.2006
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

PROBLEM TO BE SOLVED: To provide a medicinal composition of treating acute or chronic renal disease such as renal failure or dysfunction. SOLUTION: The composition contains an EP 4 receptor selective prostaglandin (PGE2) agonist, especially a pyrrolidone derivative such as 5-(3-hydroxy-4-phenyl-but-...