USE OF PROSTAGLANDIN (PGE2) RECEPTOR 4 (EP4) SELECTIVE AGONIST FOR TREATMENT OF ACUTE AND CHRONIC RENAL FAILURE
PROBLEM TO BE SOLVED: To provide a medicinal composition of treating acute or chronic renal disease such as renal failure or dysfunction. SOLUTION: The composition contains an EP 4 receptor selective prostaglandin (PGE2) agonist, especially a pyrrolidone derivative such as 5-(3-hydroxy-4-phenyl-but-...
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| Main Authors | , |
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| Format | Patent |
| Language | English |
| Published |
13.07.2006
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| Subjects | |
| Online Access | Get full text |
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| Abstract | PROBLEM TO BE SOLVED: To provide a medicinal composition of treating acute or chronic renal disease such as renal failure or dysfunction. SOLUTION: The composition contains an EP 4 receptor selective prostaglandin (PGE2) agonist, especially a pyrrolidone derivative such as 5-(3-hydroxy-4-phenyl-but-1-enyl)-1-[6-(1H-tetrazol-5-yl)-hexyl]-pyrrolidin-2-one, 5-(3-hydroxy-4-phenyl-butyl)-1-[6-(1H-tetrazol-5-yl)-hexyl]-pyrrolidin-2-one and 7-[2-(3-hydroxy-4-phenyl-but-1-enyl)-5-oxo-pyrrolidin-1-yl]-heptanoic acid. COPYRIGHT: (C)2006,JPO&NCIPI |
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| AbstractList | PROBLEM TO BE SOLVED: To provide a medicinal composition of treating acute or chronic renal disease such as renal failure or dysfunction. SOLUTION: The composition contains an EP 4 receptor selective prostaglandin (PGE2) agonist, especially a pyrrolidone derivative such as 5-(3-hydroxy-4-phenyl-but-1-enyl)-1-[6-(1H-tetrazol-5-yl)-hexyl]-pyrrolidin-2-one, 5-(3-hydroxy-4-phenyl-butyl)-1-[6-(1H-tetrazol-5-yl)-hexyl]-pyrrolidin-2-one and 7-[2-(3-hydroxy-4-phenyl-but-1-enyl)-5-oxo-pyrrolidin-1-yl]-heptanoic acid. COPYRIGHT: (C)2006,JPO&NCIPI |
| Author | THOMPSON DAVID DUANE PARALKAR VISHWAS MADHAV |
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| Snippet | PROBLEM TO BE SOLVED: To provide a medicinal composition of treating acute or chronic renal disease such as renal failure or dysfunction. SOLUTION: The... |
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| Title | USE OF PROSTAGLANDIN (PGE2) RECEPTOR 4 (EP4) SELECTIVE AGONIST FOR TREATMENT OF ACUTE AND CHRONIC RENAL FAILURE |
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