BIPHENYL COMPOUND

PROBLEM TO BE SOLVED: To obtain a compound having agonist activity to peroxisome proliferator-activated receptor δ (PPARδ) and useful as an agent for raising the blood concentration of high density lipoprotein (HDL), therapeutic agent for low HDL lipoproteinemia and/or treating agent for arterioscle...

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Bibliographic Details
Main Authors MIYAUCHI HIROSHI, UCHIYAMA KATSUYA, UNO SHINSAKU
Format Patent
LanguageEnglish
Published 07.07.2005
Edition7
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PROBLEM TO BE SOLVED: To obtain a compound having agonist activity to peroxisome proliferator-activated receptor δ (PPARδ) and useful as an agent for raising the blood concentration of high density lipoprotein (HDL), therapeutic agent for low HDL lipoproteinemia and/or treating agent for arteriosclerosis. SOLUTION: There is provided a compound represented by formula (1) (wherein R1to R8are each H, hydroxy, a 1-6C alkyl which may have a substituent, or the like; R9and R10are each H, a 1-6C alkyl which may have a substituent; R11and R12are each H, F, a 1-6C alkyl which may have a substituent, or the like; W1and W2are each O, S, or the like; and R13is carboxy, a 2-7C alkoxycarbonyl which may have a substituent, or the like, provided that at least one of R9and R10is not H, or they are not H at the same time) or its salt. COPYRIGHT: (C)2005,JPO&NCIPI
Bibliography:Application Number: JP20030423747