ARILETERI DELLE N-ALCHIL-PIPERIDINE E LORO SALI DI ADDIZIONE CON ACIDI

• Main Authors: AINA LISBETH ABRAMO, ANDRES KARL, BENGT ERIC, BJORK KONRAD, KUELLBERG SIGVARD
• Format: Patent
• Language: Italian
• Published: 28.09.1985
• Edition: 4
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Aryl ethers of N-alkyl-piperdines having the formula I wherein R1 represents hydrogen, halogen including F, Cl and Br, a lower alkanoyl group (e.g. alkanoyl of up to five carbon atoms), an alkenyl group (having three to five carbon atoms) or phenoxy, R2 represents hydrogen, halogen including F, Cl and Br, -CN group, a lower alkoxy group (e.g. alkoxy of up to five carbon atoms), a lower alkanoyl group (e.g. alkanoyl of up to five carbon atoms), an alkenyloxy or alkynyloxy group (having three to five carbon atoms) or a lower alkoxycarbonyl group (e.g. alkoxycarbonyl of up to five carbon atoms), R3 and R4 independently represent hydrogen, halogen including F, Cl and Br, a -CF3 group, a lower alkyl group (e.g. alkyl of up to five carbon atoms) or a lower alkoxy group (e.g. alkoxy of up to five carbon atoms), R5 represents hydrogen or an acyl group with 2-19 carbon atoms and n=3 or 4, and pharmaceutically acceptable acid addition salts. Pharmaceutical compositions containing said substances. Said substances are active in the central nervous system.