2-(pýridín-2-ýlamínó)-pýridó[2,3-d]pýrimidín-7-ón

• Main Authors: JOSEPH THOMAS REPINE, PETER LAURENCE TOOGOOD, RICHARD JOHN BOOTH, MARK ROBERT BARVIAN, HAIRONG ZHOU, SCOTT NORMAN VANDERWEL, DEREK JAMES SHEEHAN, JOHN QUIN III
• Format: Patent
• Language: Icelandic
• Published: 16.06.2004
• Edition: 7
• Subjects: ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM; CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention provides substituted 2-aminopyridines useful in treating cell proliferative disorders. The novel compounds of the present invention are potent inhibitors of cyclin-dependent kinases 4 (cdk4).