Einræktuð mótefni úr mönnum gegn CTLA-4
In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucleotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, particularly contiguous heavy and...
Saved in:
Main Authors | , , , , , , |
---|---|
Format | Patent |
Language | Icelandic |
Published |
15.08.2012
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucleotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, particularly contiguous heavy and light chain sequences spanning the complementarity determining regions (CDRs), specifically from within FR1 and/or CDR1 through CDR3 and/or within FR4, are provided. Further provided are antibodies having similar binding properties and antibodies (or other antagonists) having similar functionality as antibodies disclosed herein. |
---|---|
AbstractList | In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucleotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, particularly contiguous heavy and light chain sequences spanning the complementarity determining regions (CDRs), specifically from within FR1 and/or CDR1 through CDR3 and/or within FR4, are provided. Further provided are antibodies having similar binding properties and antibodies (or other antagonists) having similar functionality as antibodies disclosed herein. |
Author | JEFFREY HERBERT HANKE STEVEN CHRISTOPHER GILMAN C. GEOFFREY DAVIS DOUGLAS CHARLES HANSON MARK JOSEPH NEVEU JOSE RAMON CORVALAN EILEEN ELLIOT MUELLER |
Author_xml | – fullname: STEVEN CHRISTOPHER GILMAN – fullname: DOUGLAS CHARLES HANSON – fullname: JEFFREY HERBERT HANKE – fullname: C. GEOFFREY DAVIS – fullname: JOSE RAMON CORVALAN – fullname: MARK JOSEPH NEVEU – fullname: EILEEN ELLIOT MUELLER |
BookMark | eNrjYmDJy89L5WTQcc3MKzq8LLuk9PAGhdzDm0tS0_IyFQ7vKgJytuXlleYqpKem5yk4h_g46prwMLCmJeYUp_JCaW4GWTfXEGcP3dSC_PjU4oLE5NS81JJ4z2Ajc0sLJydjQvIAW7csiQ |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences Forestry Agriculture Physics |
ExternalDocumentID | IS2798BB |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_IS2798BB3 |
IEDL.DBID | EVB |
IngestDate | Fri Jul 19 13:13:48 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | Icelandic |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_IS2798BB3 |
Notes | Application Number: IS20010005974 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120815&DB=EPODOC&CC=IS&NR=2798B |
ParticipantIDs | epo_espacenet_IS2798BB |
PublicationCentury | 2000 |
PublicationDate | 20120815 |
PublicationDateYYYYMMDD | 2012-08-15 |
PublicationDate_xml | – month: 08 year: 2012 text: 20120815 day: 15 |
PublicationDecade | 2010 |
PublicationYear | 2012 |
RelatedCompanies | PFIZER, INC AMGEN FREMONT INC |
RelatedCompanies_xml | – name: AMGEN FREMONT INC – name: PFIZER, INC |
Score | 2.863712 |
Snippet | In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4).... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY CARE OF BIRDS, FISHES, INSECTS CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NEW BREEDS OF ANIMALS NEW PLANTS OR PROCESSES FOR OBTAINING THEM ORGANIC CHEMISTRY PEPTIDES PHYSICS PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING TRAPPING VINEGAR WINE |
Title | Einræktuð mótefni úr mönnum gegn CTLA-4 |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120815&DB=EPODOC&locale=&CC=IS&NR=2798B |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQAR2RZgJsBgCzuJGJrkmikYUusN1sqWuaCqwsjBOBHQhD0N5hXz8zj1ATrwjTCCaGVNheGPA5oeXgwxGBOSoZmN9LwOV1AWIQywW8trJYPykTKJRv7xZi66IG7R0bGgFrOFM1Fydb1wB_F39nNWdnW89gNb8gWyNzSwsnZgZWUAsadMS-a5gTaENKAXJt4ibIwBYANCivRIiBKbNYmIHbMb0IegJGqjADpzPsCjZhBg7QxZlQpi90ElyYgR28ajMZqJMDmjOLRRh0XDPzig4vyy4pPbxBIffw5pLUtLxMhcO7ioCcbXl5pbkK6anpeQrOIT6OuiaiDLJuriHOHrpAl8XDQyDeMxjsfidjMQaWvPy8VAkGhaQUS2Njw2RjoxTQ2kDzZIs0Q8vERMOkFNB57KYGJpIMYtjNkMIlIc3ABQpB0ICpoakMA0tJUWmqLLDGLUmSA4cXAAjShyw |
link.rule.ids | 230,309,786,891,25594,76904 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQAR2RZgJsBgCzuJGJrkmikYUusN1sqWuaCqwsjBOBHQhD0N5hXz8zj1ATrwjTCCaGVNheGPA5oeXgwxGBOSoZmN9LwOV1AWIQywW8trJYPykTKJRv7xZi66IG7R0bGgFrOFM1Fydb1wB_F39nNWdnW89gNb8gWyNzSwsnZgZWc2BvEHTEvmuYE2hDSgFybeImyMAWADQor0SIgSmzWJiB2zG9CHoCRqowA6cz7Ao2YQYO0MWZUKYvdBJcmIEdvGozGaiTA5ozi0UYdFwz84oOL8suKT28QSH38OaS1LS8TIXDu4qAnG15eaW5Cump6XkKziE-jromogyybq4hzh66QJfFw0Mg3jMY7H4nYzEGlrz8vFQJBoWkFEtjY8NkY6MU0NpA82SLNEPLxETDpBTQeeymBiaSDGLYzZDCJSHPwOkR4usT7-Pp5y3NwAUKTdDgqaGpDANLSVFpqiyw9i1JkgOHHQCBN4oX |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=Einr%C3%A6ktu%C3%B0+m%C3%B3tefni+%C3%BAr+m%C3%B6nnum+gegn+CTLA-4&rft.inventor=STEVEN+CHRISTOPHER+GILMAN&rft.inventor=DOUGLAS+CHARLES+HANSON&rft.inventor=JEFFREY+HERBERT+HANKE&rft.inventor=C.+GEOFFREY+DAVIS&rft.inventor=JOSE+RAMON+CORVALAN&rft.inventor=MARK+JOSEPH+NEVEU&rft.inventor=EILEEN+ELLIOT+MUELLER&rft.date=2012-08-15&rft.externalDBID=B&rft.externalDocID=IS2798BB |