Modulators of a potassium channel and of trpv1 channel and uses thereof
Compounds represented by Formula I: (I) wherein A, B, W, V, Z, Ra, Rb, n and m are as defined in the instant specification, or by Formula la, lb, III, IV or V, as defined in the instant specification, and uses thereof in modulating an activity of a voltage-dependent potassium channel and/or a TRPV1...
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| Main Authors | , , , |
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| Format | Patent |
| Language | English Hebrew |
| Published |
01.09.2024
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| Abstract | Compounds represented by Formula I: (I) wherein A, B, W, V, Z, Ra, Rb, n and m are as defined in the instant specification, or by Formula la, lb, III, IV or V, as defined in the instant specification, and uses thereof in modulating an activity of a voltage-dependent potassium channel and/or a TRPV1 channel and in treating a medical condition associated with an activity of these channels, such as medical conditions associated with neuronal hyper-excitability, are provided. |
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| AbstractList | Compounds represented by Formula I: (I) wherein A, B, W, V, Z, Ra, Rb, n and m are as defined in the instant specification, or by Formula la, lb, III, IV or V, as defined in the instant specification, and uses thereof in modulating an activity of a voltage-dependent potassium channel and/or a TRPV1 channel and in treating a medical condition associated with an activity of these channels, such as medical conditions associated with neuronal hyper-excitability, are provided. |
| Author | Adi RAVEH Alan Daniel BROWN Haim BELINSON Alon SILBERMAN |
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| Discipline | Medicine Chemistry Sciences |
| DocumentTitleAlternate | חומרים המשפיעים על תעלת אשלגן ותעלת trpv1 ושימושיהם |
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| Notes | Application Number: IL20240314405 |
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| RelatedCompanies | Adi RAVEH Alan Daniel BROWN Haim BELINSON Alon SILBERMAN BSENSE BIO THERAPEUTICS LTD |
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| Snippet | Compounds represented by Formula I: (I) wherein A, B, W, V, Z, Ra, Rb, n and m are as defined in the instant specification, or by Formula la, lb, III, IV or V,... |
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| Title | Modulators of a potassium channel and of trpv1 channel and uses thereof |
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