Crystalline forms of a monoacylglycerol lipase inhibitor

Described herein are new crystalline forms of the MAGL inhibitor 1-(1-(2-(pyrrolidin-1-yl)-4-(trifluoromethyl)b enzyl)-1,8-diazaspiro[4.5]decane-8-carbonyl)-1H-pyrazole-3-carboxylic acid, or a pharmaceutically acceptable salt thereof.

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Bibliographic Details
Main Authors LOPEZ DE DIEGO Heidi, GRICE Cheryl A, ALLAN Amy, WIENER John J.M, BUZARD Daniel J, VETTER Thomas, EDWARDS Richard James, ANDREW Samuel George, GANCEDO Susana Del Rio, PATTERSON Adam Ross, CINCOTTI Antonio, JUHL Martin
Format Patent
LanguageEnglish
Hebrew
Published 01.05.2024
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Described herein are new crystalline forms of the MAGL inhibitor 1-(1-(2-(pyrrolidin-1-yl)-4-(trifluoromethyl)b enzyl)-1,8-diazaspiro[4.5]decane-8-carbonyl)-1H-pyrazole-3-carboxylic acid, or a pharmaceutically acceptable salt thereof.
Bibliography:Application Number: IL20240311850