Treatment and inhibition of fibrosis in non-alcoholic fatty liver disease patients
The invention relates to the treatment, inhibition and reduction of fibrosis, including hepatic fibrosis. More specifically, the invention provides compositions and methods useful for the treatment and inhibition of fibrotic disorders, hepato-fibrotic conditions associated with Non-Alcoholic Fatty L...
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| Main Authors | , , , |
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| Format | Patent |
| Language | English Hebrew |
| Published |
01.12.2021
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| Online Access | Get full text |
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| Abstract | The invention relates to the treatment, inhibition and reduction of fibrosis, including hepatic fibrosis. More specifically, the invention provides compositions and methods useful for the treatment and inhibition of fibrotic disorders, hepato-fibrotic conditions associated with Non-Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH), employing the use of 3β-arachidylamido-7α,12α-dihydroxy-5β-cholan-24-oic acid (AramcholTM) or a pharmaceutically acceptable salt thereof in a dose having an advantageous systemic exposure. |
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| AbstractList | The invention relates to the treatment, inhibition and reduction of fibrosis, including hepatic fibrosis. More specifically, the invention provides compositions and methods useful for the treatment and inhibition of fibrotic disorders, hepato-fibrotic conditions associated with Non-Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH), employing the use of 3β-arachidylamido-7α,12α-dihydroxy-5β-cholan-24-oic acid (AramcholTM) or a pharmaceutically acceptable salt thereof in a dose having an advantageous systemic exposure. |
| Author | ALLEN BAHARAFF MATO DE LA PAZ Jose M LIAT HAYARDENY-NISIMOV GORFINE TALI |
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| DocumentTitleAlternate | טיפול ומניעת פיברוסיס בחולי מחלות כבד שומני לא אלכוהולי |
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| RelatedCompanies | GALMED RESEARCH AND DEVELOPMENT LTD ALLEN BAHARAFF MATO DE LA PAZ Jose M LIAT HAYARDENY-NISIMOV GORFINE TALI |
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| Snippet | The invention relates to the treatment, inhibition and reduction of fibrosis, including hepatic fibrosis. More specifically, the invention provides... |
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| Title | Treatment and inhibition of fibrosis in non-alcoholic fatty liver disease patients |
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