TRISUBSTITUTED PYRIMIDO [5,4-D] PYRIMIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PRODUCING THEM

The invention relates to trisubstituted pyrimido [5,4-d]-pyrimidines of general formula (I) (wherein Ra, Rb and Rc are defined as in claim 1) and the salts thereof, more particularly for pharmaceutical use the physiologically acceptable salts thereof, which have, inter alia, valuable pharmacological...

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Main Authors BAMBERGER,UWE, HECKEL,ARMIN, MAUZ,ANNEROSE
Format Patent
LanguageEnglish
Published 28.11.1995
Edition5
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract The invention relates to trisubstituted pyrimido [5,4-d]-pyrimidines of general formula (I) (wherein Ra, Rb and Rc are defined as in claim 1) and the salts thereof, more particularly for pharmaceutical use the physiologically acceptable salts thereof, which have, inter alia, valuable pharmacological properties, particularly in chemotherapy a sensitizing effect on resistant tumors, the use thereof and processes for preparing them.
AbstractList The invention relates to trisubstituted pyrimido [5,4-d]-pyrimidines of general formula (I) (wherein Ra, Rb and Rc are defined as in claim 1) and the salts thereof, more particularly for pharmaceutical use the physiologically acceptable salts thereof, which have, inter alia, valuable pharmacological properties, particularly in chemotherapy a sensitizing effect on resistant tumors, the use thereof and processes for preparing them.
Author MAUZ,ANNEROSE
BAMBERGER,UWE
HECKEL,ARMIN
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Snippet The invention relates to trisubstituted pyrimido [5,4-d]-pyrimidines of general formula (I) (wherein Ra, Rb and Rc are defined as in claim 1) and the salts...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title TRISUBSTITUTED PYRIMIDO [5,4-D] PYRIMIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PRODUCING THEM
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