PROCESS FOR PRODUCING OPTICAL ISOMERS OF N-[2-HYDROXI-3-(PIPERIDIN-1-YL)-PROPOXY]-OXIMETHERS BY RESOLVING THE RACEMIC COMPOUND AND OPTICAL ISOMERS OF O-(3-N-PIPERIDINO-2 HIDROXY-1-PROPYL)-NICOTINIC ACID AMIDOXIM (NP51)

• Main Authors: SZEKELY ISTVAN, TARY MARIA, JANOSI AGNES, BERTOK BELA
• Format: Patent
• Language: English; Hungarian
• Published: 28.02.2001
• Edition: 7

Optical isomers of N-(2-hydroxy-3-(piperidine-1-yl)-propoxy)-oxime-ethers are resolved from their racemic mixt. with optically active cyclo-propane-carboxylic acid, or its salt, resolving agent - where (y) substituents are Cl atom or a methyl gp.. Occasionally salts of this acid are prepd. by direct...