FACTOR VIII CHIMERIC PROTEINS AND USES THEREOF

• Main Authors: CHHABRA, Ekta Seth, LIU, Tongyao
• Format: Patent
• Language: English; Hungarian
• Published: 28.12.2022
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The present invention provides a chimeric protein comprising a first polypeptide which comprises a FVIII protein and a first Ig constant region or a portion thereof and a second polypeptide which comprises a VWF protein comprising the D' domain and D3 domain of VWF, a XTEN sequence having less...