Gastroretentive drug formulation and delivery systems and their method of preparation using functionalized calcium carbonate

An instantly floating gastroretentive drug formulation comprising at least one functionalized natural and/or synthetic calcium carbonate-comprising mineral and at least one pharmaceutically active ingredient and at least one formulating aid wherein said functionalized natural or synthetic calcium ca...

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Bibliographic Details
Main Authors Puckhov, Maxim, Huwyler, Joerg, Gane, Patrick Arthur Charles, Gerard, Daniel Edward, Eberle, Veronika Anna, Schoelkopf, Joachim, Alles, Rainer
Format Patent
LanguageEnglish
Hungarian
Published 28.04.2016
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Summary:An instantly floating gastroretentive drug formulation comprising at least one functionalized natural and/or synthetic calcium carbonate-comprising mineral and at least one pharmaceutically active ingredient and at least one formulating aid wherein said functionalized natural or synthetic calcium carbonate is a reaction product of natural or synthetic calcium carbonate with carbon dioxide and one or more acids, wherein the carbon dioxide is formed in situ by the acid treatment and/or is supplied from an external source.
Bibliography:Application Number: HUE12188419