GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
The invention relates to inhibitors of glucosylceramide synthase (GCS) of formula (I) useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, cystic disease and for the treatment of cancer.
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Main Authors | , , , , , , , , , , , , , , , , , |
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Format | Patent |
Language | Croatian English |
Published |
13.05.2022
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Abstract | The invention relates to inhibitors of glucosylceramide synthase (GCS) of formula (I) useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, cystic disease and for the treatment of cancer. |
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AbstractList | The invention relates to inhibitors of glucosylceramide synthase (GCS) of formula (I) useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, cystic disease and for the treatment of cancer. |
Author | Hirth, Bradford Husson, Herve Bourque, Elyse Scheule, Ronald K Cheng, Seng H Metz, Markus Leonard, John Beskrovnaya, Oxana Makino, Elina Xiang, Yibin Natoli, Thomas Skerlj, Renato Zhao, Zhong Jancsics, Katherine Good, Andrew Cabrera-Salazar, Mario A Celatka, Cassandra Marshall, John |
Author_xml | – fullname: Good, Andrew – fullname: Makino, Elina – fullname: Cheng, Seng H – fullname: Husson, Herve – fullname: Leonard, John – fullname: Celatka, Cassandra – fullname: Marshall, John – fullname: Beskrovnaya, Oxana – fullname: Scheule, Ronald K – fullname: Xiang, Yibin – fullname: Skerlj, Renato – fullname: Jancsics, Katherine – fullname: Cabrera-Salazar, Mario A – fullname: Natoli, Thomas – fullname: Bourque, Elyse – fullname: Zhao, Zhong – fullname: Hirth, Bradford – fullname: Metz, Markus |
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DocumentTitleAlternate | INHIBITORI GLUKOZILCERAMID SINTAZE |
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Notes | Application Number: HR2022P000310T |
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RelatedCompanies | Genzyme Corporation |
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Snippet | The invention relates to inhibitors of glucosylceramide synthase (GCS) of formula (I) useful for the treatment of metabolic diseases, such as lysosomal storage... |
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Title | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS |
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