CARBIDOPA AND L-DOPA PRODRUGS AND THEIR USE TO TREAT PARKINSON'S DISEASE

• Main Authors: Henry, Rodger F, Ho, Raimundo, Huang, Ye, Dempah, Kassibla E, Chan, Vincent S, Cardinal-David, Benoit, Wang, Zhi, Zhang, Geoff G, Stella, Valentino J, Huters, Alexander D, Krabbe, Scott W, Lao, Yanbin, Mayer, Peter T, Enright, Brian P, Lou, Xiaochun, Mackey, Sean E, Matulenko, Mark A, Stambuli, James, Miller, Christopher P, Voight, Eric A, Klix, Russell C, Kym, Philip R
• Format: Patent
• Language: Croatian; English
• Published: 18.10.2019
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dop...