PRIMARY CARBOXAMIDES AS BTK INHIBITORS

The invention provides compounds of Formula (I)pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.

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Main Authors Frank, Kristine E, Osuma, Augustine, Van Epps, Stacy A, Wang, Zhi, Bonafoux, Dominique, Huntley, Raymond, Sheppard, George, Van Camp, Jennifer, Davis, Heather M, Xu, Xiangdong, Friedman, Michael M, Wallace, Grier A, Vasudevan, Anil, Somal, Gagandeep K, Hoemann, Michael Z, Wilson, Noel S, Wang, Lu, Herold, J. Martin
Format Patent
LanguageCroatian
English
Published 22.02.2019
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Abstract The invention provides compounds of Formula (I)pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
AbstractList The invention provides compounds of Formula (I)pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
Author Osuma, Augustine
Sheppard, George
Herold, J. Martin
Frank, Kristine E
Vasudevan, Anil
Wang, Zhi
Huntley, Raymond
Davis, Heather M
Van Epps, Stacy A
Somal, Gagandeep K
Wilson, Noel S
Bonafoux, Dominique
Wallace, Grier A
Wang, Lu
Xu, Xiangdong
Friedman, Michael M
Hoemann, Michael Z
Van Camp, Jennifer
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– fullname: Osuma, Augustine
– fullname: Van Epps, Stacy A
– fullname: Wang, Zhi
– fullname: Bonafoux, Dominique
– fullname: Huntley, Raymond
– fullname: Sheppard, George
– fullname: Van Camp, Jennifer
– fullname: Davis, Heather M
– fullname: Xu, Xiangdong
– fullname: Friedman, Michael M
– fullname: Wallace, Grier A
– fullname: Vasudevan, Anil
– fullname: Somal, Gagandeep K
– fullname: Hoemann, Michael Z
– fullname: Wilson, Noel S
– fullname: Wang, Lu
– fullname: Herold, J. Martin
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DocumentTitleAlternate PRIMARNI KARBOKSAMIDI KAO INHIBITORI BTK
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Snippet The invention provides compounds of Formula (I)pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Title PRIMARY CARBOXAMIDES AS BTK INHIBITORS
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